gp130 receptor cytokines stat3 depicting hypertrophy ras bind signaling binding ligand stat phosphorylation pathways pi3k raf proteins subunits cytoplasmic phosphorylated
gp130 signalling tyrosine representation distinct schematic residues shp ras erk
gp130 pathway signaling cytokines stat1 mediated stat3 activation phosphorylation shp
lifr gp130 receptor signal transduction pathways complex lif
gp130 activation constitutive cytokine leads dimerization stem blockade stat3 differentiation embryonic cells
receptor interleukin signal gp130 transduction complex tocilizumab mechanism soluble
interleukin signal transduction receptor gp130
transduction signal ligand interactions representation receptor gpcrs
transduction activated mechanisms npy pathways mitogenic kinase
gp130 receptor complexes composition structural ligands ligand
cell chimeric receptors comparison lysates