gp130 receptor cytokines stat3 depicting hypertrophy ras bind signaling binding ligand stat phosphorylation pathways pi3k raf proteins subunits cytoplasmic phosphorylated
cardiomyocytes phosphatase gab1 interaction gp130 transduces shp2 scaffolding tyrosine protein docking activation
gp130 osm signaling receptor stat3 response mapk pi3k
gab1 cardiomyocytes powerpoint shp2 phosphatase scaffolding transduces signal gp130 hypertrophic activation tyrosine docking
calcineurin pathway signaling akt pi3k activation mechanism gp130 stat mtor kinase ras
stat3 activation transcription activator transducer
gp130 wiley figure potential pathways mediated aspects therapeutic signalling role impact heart its
gp130 receptor complexes composition structural ligands ligand
signals activation hypertrophic myocytes gp130 stat3 transduces cardiac ahajournals
activation signals hypertrophic gp130 transduces stat3 cardiac myocytes
hypertrophic activation signals transduces cardiac stat3 myocytes gp130